Extract of an anti-cancer compound from bovine chamomile flowers
Scientists at the University of Birmingham have recently discovered that bovine chamomile has an anti-cancer compound.
Feverfew is a common flower with a high frequency that can be easily seen everywhere from a home garden to store pots.
It has been used as a traditional medicine for hundreds of years to treat migraines and other aches and pains, although its usefulness is questionable.
But now researchers at the University of Birmingham have engineered a combination of the plant’s leaves that could be a potential and powerful cancer killer.
The compound in question is called parthenolide and this type of research has been done for years.
Scientists at the University of Birmingham sought to prove that the substance was anti-cancer, and they succeeded, but eventually found it difficult and expensive to obtain beneficial amounts of the compound.
Bovine chamomile and related plants have a lot of parthenolide, so the University of Birmingham research team sought to find the best candidate to extract this compound, and after a few experiments found that the best host of this compound is bovine chamomile itself, which has the highest level of this substance.
The researchers then succeeded in extracting the compound from the flower, refining it and turning it into new derivatives that are good candidates for anti-cancer drugs.
Of the 76 copies that were extracted, the group eventually offered one that is biocompatible, meaning that it can react with living cells and have many better pharmacological properties.
The compound has been used to fight a type of cancer called chronic lymphocytic leukemia (CLL) and has been shown to be effective in experiments on cultured cancer cells.
Chronic lymphocytic leukemia is a type of leukemia. This type of leukemia affects the lymph cells or lymphocytes that make up the lymph tissue and has a chronic course.
This compound destabilizes unstable molecules that can be toxic to cells by raising the level of reactive oxygen species (ROS). Reactive oxygen species are also being studied as potential antibacterial agents, and because they are now more abundant in cancer tissue than in healthy cells, the compound puts pressure on them.
This research is important not only because we have found a way to produce parthenolide that can make it more accessible to researchers, but also because we have been able to improve its medicinal properties, said John Fossi, one of the study’s researchers. Improve to kill cancer cells. It is now clear that parthenolide has the ability to deliver bovine chamomile flowers to the laboratory.
The next steps will be to test this compound in live animals and eventually in humans.
Bovine chamomile with the scientific name Tanacetum parthenium is a species of enamel genus and is a medicinal plant that is used in the treatment of migraine and some inflammatory diseases. This flower is extremely agile and is good for relieving headaches.
Cow chamomile grows in the highlands of Iran, including at altitudes above 2500 meters in Kohgiluyeh and Boyer-Ahmad provinces and in the village of Lind Savadkuh with an altitude of 2000 meters in Mazandaran province.
The extract obtained from this medicinal plant is obtained from its flowering branches. The active ingredient in this extract is Parthenol, which has anti-inflammatory, anti-spasmodic and anti-migraine effects, and its anti-cancer properties have already been discovered.
