Pistachio gum is a hypnotic and anti-anxiety extract

Pistachio gum is a hypnotic and anti-anxiety extract

The results of a study in the animal phase showed that the hydroalcoholic extract of pistachio gum has a positive effect on facilitating the hypnotic process, anti-anxiety effect and muscle relaxation.
Hossein Hosseinzadeh, Professor of Pharmacodynamics and Toxicology, Center for Pharmaceutical Sciences Research and School of Pharmacy, Mashhad University of Medical Sciences, has studied the effects of intraperitoneal injection of hydroalcoholic extract of pistachio gum on muscle relaxation, sleep and anxiety in mice.
In this study, the effect of pistachio gum on motor balance and muscle relaxation was investigated by rotating and horizontal bar methods, 30 and 60 minutes after injection. In the hypnotic test, the time of onset of sleep and the duration of sleep were 30 minutes after injection of extracts and substances by induction of sleep by pentobarbital injection. Mice behaviors of mice were evaluated by open box test and anti-anxiety effect by plus maze method, 30 minutes after injection.
The results show that pistachio gum at doses of 11 and 0.5-2.5 g / kg had significant hypnotic effects (increase during sleep in all doses and decrease in sleep onset at 1 g / kg), effect Anxiety in the maze test, in addition, had muscle relaxation (in the horizontal test at a dose of 1 g / kg) and decreased motor activity with all doses.
The results of this study indicate that the hydroalcoholic extract of pistachio gum has a good effect on facilitating the process of drowsiness, anti-anxiety effect and muscle relaxation, which may be effective in reducing muscle contraction disorders, insomnia and anxiety.