Cumin fruit is effective in reducing acute and chronic pain

Cumin fruit is effective in reducing acute and chronic pain

The results of a study indicate the reduction of acute and chronic pain using aqueous extract of cumin fruit.

Abbas Ali Taherian, an instructor at the Physiology Research Center of Semnan University of Medical Sciences, has conducted a study with the aim of investigating the analgesic effects of cumin fruit aqueous extract on neurogenic and inflammatory pain in formalin test in mice.

In this study, 50 male albino mice weighing 25 to 30 grams were used. Aqueous extract of cumin fruit – 200, 500 and 1000 mg / kg body weight – and the same amount of saline were injected intraperitoneally 30 minutes before formalin test.
Criteria for evaluating pain in formalin test were the duration of licking and keeping them high in acute stages – the first 5 minutes – and chronic – 15 to 40 minutes – after injecting formalin – 25 microliters of 5% solution – in the sole of the foot.

The results of this study showed that the aqueous extract of cumin fruit significantly reduced the response of animals to painful stimuli, this effect was greater in the acute phase at a dose of 200 mg, while in the chronic phase with a higher dose, ie with a dose 1000 mg / kg body weight was more pronounced.

There was no significant difference in pain response between the control group and the saline group.